the presence of anemia was significantly associated with a higher likelihood of having insomnia in adults. [7–10] however, to the best of our knowledge, only three studies to date have examined the relationship between anemia and insomnia in the adult population, and all three reported that anemia was associated with insomnia. each question is scored on a scale of 0 to 3, with 0 being no problem of the corresponding sleep parameter and 3 being a serious problem (occurrence of greater than three times a week in the past month). blood pressure (bp) was measured twice in the seated position using a mercury sphygmomanometer; the average of the two readings was used for analyses. approximately 4.3% of the population was defined to have anemia based on hemoglobin levels and 15.2% of the population reported having insomnia [table [table1].1]. this may lead to overestimating the association between anemia and insomnia [figure [figure33].
this finding is of clinical and public health importance due to the high prevalence of anemia and insomnia.  another potential mechanism of this phenomenon may be explained by altered blood flow in the brain, which was associated with both anemia and insomnia. in this context, further prospective studies are warranted to elucidate the temporal relationship between anemia and insomnia. for example, the prevalence of anemia was lower, relative to the estimated 9.7% in a national survey. doi: 10.1097/cm9.0000000000001306 the ors and 95% cis of insomnia according to four anemia groups. ci: confidence interval; or: odds ratio.
the presence of anemia was significantly associated with a higher likelihood of having insomnia in adults. due to the nature of the cross- anemia is associated with poorer sleep in children, and clinically, anemia is linked to insomnia. however, the association between anemia and insomnia in older we’ve seen research showing iron-deficiency anemia is linked to lower sleep quality, and a small group of studies showing an association between, .
notably, the presence of prior anemia increased the risk of developing insomnia 6 years later by 32% compared to those without anemia. in addition, severe anemia significantly increased the odds of insomnia relative to mild and moderate anemia. the risk was found to be higher in men than in women. does anemia affect sleep? a number of research studies indicate that the answer is yes, there is a strong correlation between iron deficiency and sleep problems. the overlap of the same brain region linked to both hemoglobin levels and shorter sleep duration may suggest a common pathway in the development insomnia, the inability to fall or stay asleep, is not a direct symptom of anemia, but sleep and alertness can be affected. symptoms of fatigue and chronic severe anemia was strongly linked to increased risk for insomnia while mild and moderate anemia was also associated with an elevated insomnia, .
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