bri is powering discoveries to prevent and treat immune system diseases and rebalance the immune system. some of the diseases we study include type 1 diabetes, rheumatoid arthritis, lupus, multiple sclerosis, crohn’s and colitis as well as allergies, cancer and covid-19. there are approximately 110+ different types of autoimmune diseases and they affect more than 23 million americans. type 1 diabetes (t1d) is an autoimmune disease in which the body’s immune system attacks and destroys the beta cells in the pancreas that make insulin. multiple sclerosis (ms) is an autoimmune disease in which the body’s immune system mistakenly attacks myelin, the fatty substance that surrounds and protects the nerve fibers in the central nervous system.
rheumatoid arthritis (ra) is an autoimmune disease in which the body’s immune system mistakenly attacks its own tissues, primarily the synovium, the membrane that lines the joints. allergies and asthma are immune mediated diseases that occur when the body’s immune system overreacts to a foreign substance (an allergen), such as pollen or animal dander, that in most people is generally harmless. in addition, 2.5 million americans are undiagnosed and may be at risk for long-term health complications. it is a rare disease in which the immune system attacks the body’s cartilage. there are many diseases and disorders that can cause the liver to stop functioning properly. cancer represents more than 200 different types of malignancies—diseases caused by the uncontrolled and destructive growth of cells.
your immune system can tell that the germs aren’t part of you, so it destroys them. if you have an autoimmune disease, your immune system attacks the healthy cells of your organs and tissues by mistake. for example, alopecia areata is an autoimmune disease of the skin that causes hair loss. autoimmune hepatitis affects the liver. and in rheumatoid arthritis, the immune system can attack many parts of the body, including the joints, lungs, and eyes. viruses, certain chemicals, and other things in the environment may trigger an autoimmune disease if you already have the genes for it. and if you have one autoimmune disease, you are more likely to get another. the symptoms of an autoimmune disease depend on the part of your body that’s affected.
the symptoms of autoimmune diseases can come and go. later on, you may have a remission, which means that your symptoms get better or disappear for a period of time. there’s usually not a specific test to show whether you have a certain autoimmune disease. and the symptoms can be confusing. so it can take a long time and some visits to different types of doctors to get a diagnosis. in most cases, the goal of treatment is to suppress (slow down) your immune system, and ease swelling, redness, and pain from inflammation. for some diseases, you may need treatment for the rest of your life. contact a health care provider if you have questions about your health.
niams focuses on arthritis, musculoskeletal & skin diseases. find causes, treatment & prevention you can have paget’s disease in any bones in your body. crohn’s disease and ulcerative colitis (uc), both also known as inflammatory bowel diseases (ibd), are autoimmune diseases in which the body’s immune system an alphabetical listing of common diseases and conditions, both chronic and infectious, that affect the everyday lives of illinois residents., .
lice, body — see body lice lice, head — see head lice listeriosis — see listeria infection liver disease and hepatitis — see viral hepatitis your immune system is your body’s defense against infections and other harmful invaders. without it, you would constantly get sick from bacteria or viruses. autoimmune diseases are where your immune system attacks healthy cells in your body by mistake. learn about the symptoms, tests,, .
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