bone marrow edema is when fluid builds up in your bone marrow. the most common locations for it are your: bone marrow is soft, spongy tissue that’s in the middle of most of your bones. those are special cells that can eventually become red blood cells, white blood cells, or platelets. many types, including osteoarthritis and rheumatoid arthritis, cause bone marrow edema. as bones become weak and start to break easily, bone marrow edema is more likely. bone tumors. this can trigger edema in the marrow.
radiation treatment for cancer can also make bone marrow edema more likely. when your body fights a bone infection (your doctor may call it osteomyelitis), your tissues tend to swell. pain is usually the main sign that something is wrong. it’s common when you have edema around your knees. if your doctor thinks you may have bone marrow edema, you’ll get a physical and they’ll ask you questions about your medical history. bone marrow edema doesn’t show up on an x-ray or ct scan. in many cases, bone marrow edema will go away with rest, therapy, and pain meds like nonsteroidal anti-inflammatory drugs (nsaids). in more serious cases, your doctor may suggest other medicines and surgery.
although pain is the major symptom, bme differs in terms of its causal mechanisms, underlying disease, as well as treatment and prognosis. however, interdisciplinary, evidence-based guidelines for the diagnosis and management of bme are lacking. overall, the data for any entity of bme is sparce and predominantly limited to situations in which bme already is present. in case of an acute trauma or recent surgical intervention, the patient should be referred to an orthopedic surgeon (figure 1). the combined interpretation of the mri and ct images should be conducted by a radiologist experienced in musculoskeletal imaging. in rheumatology, bme is of great importance for the diagnosis of musculoskeletal inflammation including arthritis, spondylitis and enthesitis. if two different nsaids are insufficient to control the inflammation, biologic agents (inhibitors of tnf and il-17) are recommended. the key to successful treatment of bone stress injuries is early diagnosis [66] and identification of the nature of the injury (stress lesion (reaction), stress fracture, or instability). the diagnosis of avascular necrosis (avn) can be challenging and relies on mrt and ct imaging.
although bme is often thought to be an early sign of avn, recent studies showed that bme occurs only in late stages of the disease, i.e., arco stages iii and iv, as a sign of biomechanical deterioration of the trabecula [12,13,14,15]. bme is detectable in a significant proportion of patients with asymptomatic primary hyperparathyroidism [78]. focal peripheral edema at the growth plate, particularly observed in the knee, is attributed to early stages of growth plate closure, and may be associated with pain. the primary aim of treating bmes is a quick reduction of pain and disability, as well as dissolution of the bme [106]. to identify the underlying cause of painful bme is the paramount prerequisite to initiating the appropriate treatment. all authors have read and agreed to the published version of the manuscript. ); ed.nehcneum-inu.dem@ebuarts.saerdna (a.s.) 2department of general, trauma and reconstructive surgery, university hospital, ludwig-maximilians-university munich, nussbaumstraße 20, 80336 munich, germany 1comprehensive osteology center munich, university hospital, ludwig-maximilians-university munich, 80336 munich, germany; ed.nehcneum-inu.dem@hcabmuab.naitsabes (s.f.b. ); ed.nehcneum-inu.dem@ebuarts.saerdna (a.s.) 2department of general, trauma and reconstructive surgery, university hospital, ludwig-maximilians-university munich, nussbaumstraße 20, 80336 munich, germany 1comprehensive osteology center munich, university hospital, ludwig-maximilians-university munich, 80336 munich, germany; ed.nehcneum-inu.dem@hcabmuab.naitsabes (s.f.b. ); ed.nehcneum-inu.dem@ebuarts.saerdna (a.s.) 2department of general, trauma and reconstructive surgery, university hospital, ludwig-maximilians-university munich, nussbaumstraße 20, 80336 munich, germany 1comprehensive osteology center munich, university hospital, ludwig-maximilians-university munich, 80336 munich, germany; ed.nehcneum-inu.dem@hcabmuab.naitsabes (s.f.b. ); ed.nehcneum-inu.dem@ebuarts.saerdna (a.s.) 8department for endocrinology and diabetology, department of internal medicine iv, ludwig-maximilians-university munich, ziemssenstraße 1, 80336 munich, germany 1comprehensive osteology center munich, university hospital, ludwig-maximilians-university munich, 80336 munich, germany; ed.nehcneum-inu.dem@hcabmuab.naitsabes (s.f.b.
bone marrow edema is when fluid builds up in your bone marrow. your doctor may call it bone marrow lesions. the most common locations for it bone marrow edema syndrome is a diagnosis of exclusion that is characterized by pain and increased interstitial fluid within bone marrow bone marrow edema (bme) is a descriptive term for a common finding in magnetic resonance imaging (mri). it can occur in virtually all bones, but, .
a bone marrow edema u2014 often referred to as bone marrow lesion u2014 occurs when fluid builds up in the bone marrow. bone marrow edema is typically a response to an injury such as a fracture or conditions such as osteoarthritis. bone marrow edema usually resolves itself with rest and physical therapy. bone marrow edema is a buildup of fluid inside your bones. it can happen because of an injury such as a fracture. or it can be related to a bone marrow edema (bme) is a condition characterized by accumulation of excessive fluid in related structures of bone marrow. usually injury of the bones bone marrow edema (bme) is one of the most common findings on magnetic resonance imaging (mri) after an ankle injury but can be present even, .
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