the .gov means it’s official. the site is secure. cheyne-stokes respiration with central sleep apnea (csr-csa) is a form of periodic breathing, commonly observed in patients with heart failure (hf), in which central apneas alternate with hyperpneas that have a waxing-waning pattern of tidal volume. uniform criteria by which to diagnose a clinically significant degree of csr-csa have yet to be established.
patients with csr-csa are generally hypocapnic, with a pa(co(2)) closer than normal to the apneic threshold such that even slight augmentation in ventilation drives pa(co(2)) below threshold and triggers apnea. controversy remains as to whether csr-csa is simply a reflection of hf severity, or whether it exerts unique adverse effects on prognosis. a number of studies have examined the potential relationship between csr-csa and mortality in hf. further research is therefore needed to elucidate mechanisms which contribute to the pathogenesis of csr-csa, and to determine whether its treatment can reduce morbidity and mortality in patients with hf.
pathogenesis of obstructive and central sleep apnea. [medline]. [medline]. [medline]. [medline]. [medline]. [medline]. [medline]. [medline]. [medline]. [medline]. [medline].
[medline]. [medline]. [medline]. [medline]. [medline]. [medline]. [medline]. [medline]. [medline]. [medline]. [medline]. sat sharma, md, frcpc professor and head, division of pulmonary medicine, department of internal medicine, university of manitoba faculty of medicine; site director, respiratory medicine, st boniface general hospital, canada sat sharma, md, frcpc is a member of the following medical societies: american academy of sleep medicine, american college of chest physicians, american college of physicians-american society of internal medicine, american thoracic society, canadian medical association, royal college of physicians and surgeons of canada, royal society of medicine, society of critical care medicine, world medical associationdisclosure: nothing to disclose.
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cheyne-stokes respiration is a condition that causes abnormal breathing during sleep. this abnormal breathing often includes “apneas,” or periods of stopped csb-csa is characterized by classic a crescendo-decrescendo pattern that typically occurs with a periodicity of 45 second or greater cycles cheyne-stokes-breathing-and-obstructive-sleep-apnea-in-heart-failur sleep-disordered breathing in heart failure mode selection for positive airway pressure, agonal breathing vs cheyne-stokes, central sleep apnea.
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