this is not a complete list of side effects and others may occur. the adverse event information for lexapro in patients with gad was collected from 429 patients exposed to escitalopram and from 427 patients exposed to placebo in double-blind, placebo-controlled trials. the rate of discontinuation for adverse events in patients assigned to a fixed dose of 20 mg/day lexapro was 10%, which was significantly different from the rate of discontinuation for adverse events in patients receiving 10 mg/day lexapro (4%) and placebo (3%). table 4 shows common adverse reactions that occurred in the 20 mg/day lexapro group with an incidence that was approximately twice that of the 10 mg/day lexapro group and approximately twice that of the placebo group.
the incidence of tachycardic outliers was 0.2% in the lexapro and the placebo group. although lexapro did not potentiate the cognitive and motor effects of alcohol in a clinical trial, as with other psychotropic medications, the use of alcohol by patients taking lexapro is not recommended. in subjects who had received 21 days of 40 mg/day racemic citalopram, combined administration of citalopram and digoxin (single dose of 1 mg) did not significantly affect the pharmacokinetics of either citalopram or digoxin. combined administration of racemic citalopram (40 mg/day for 14 days) and carbamazepine (titrated to 400 mg/day for 35 days) did not significantly affect the pharmacokinetics of carbamazepine, a cyp3a4 substrate. nevertheless, caution is indicated in the coadministration of escitalopram and drugs metabolized by cyp2d6.
in healthy women with menopausal hot flashes, treatment with escitalopram at doses of 10 or 20 mg/d relative to placebo reduced insomnia symptoms and improved according to the fda, approximately 5% of people who use lexapro for anxiety or depression experience insomnia during the initial stage of the coadministration of eszopiclone and escitalopram was associated with rapid improvement in insomnia by week 1, demonstrated by changes in sleep onset,, .
insomnia as a side effect of using lexapro typically does not last long. you can expect to stop experiencing insomnia within the first two weeks of using the medication. if your insomnia persists after several weeks, talk to a doctor about other options. insomnia is a common side effect of many antidepressants, including lexapro. for example, it’s listed as one of the most common adverse reactions experienced by people prescribed lexapro in fda documentation. according to data from the fda, more than five percent of people who use lexapro experience insomnia. some antidepressants may cause insomnia, making it difficult to get to sleep or stay asleep, so you may be tired during the day. consider these strategies: take the authors reported that women treated with escitalopram had an improvement in insomnia symptoms and subjective sleep quality, drowsiness,; dizziness,; sleep problems (insomnia),; nausea,; upset stomach,; gas,; heartburn,; constipation,; weight changes,, .
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