however, the association between anemia and insomnia in older adults is understudied. a link between anemia and insomnia in older adults could have important implications for the treatment of each condition; anemia may be a modifiable contributor to insomnia, and vice versa. although there were 1,063 individuals with either iron-deficient anemia or non-iron-deficient anemia, we ultimately dropped the 10 individuals with iron-deficient anemia from our main analyses due to the low prevalence of that condition, leaving a final sample of n = 1,053 for these analyses. we also created a categorical variable representing the number of insomnia symptoms endorsed (0 insomnia symptoms, 1 symptom, or ≥2 symptoms). finally, model 4 added depressive symptoms in the form of ces-d score to model 3. restless legs syndrome may mediate the association between anemia and insomnia. to examine the association between iron/anemia status and number of insomnia symptoms, we performed a multinomial logistic regression with anemia category as a predictor and 0, 1, or 2 or more insomnia symptoms as an outcome.
model 3: adjusted for covariates in model 2 + number of chronic diseases (0, 1, 2+). model 3: adjusted for covariates in model 2 + number of chronic diseases (0, 1, 2+). (13) noted the association of both anemia and insomnia to fatigue (31–33), implying that fatigue may mediate the anemia-insomnia link. if insomnia is a marker of non-iron-deficient anemia, then identification of both anemia and insomnia may reflect medical morbidity or frailty in the older individual that needs to be addressed. in conclusion, we found that, compared to nonanemic individuals, those who were anemic (non-iron-deficient) had more severe insomnia and a greater likelihood of having two or more insomnia symptoms. it furthers the university’s objective of excellence in research, scholarship, and education by publishing worldwide
in a collaborative study published in chinese medical journal, researchers have carried out a cross-sectional analysis to understand the association between insomnia and anemia in a cohort of 12,614 chinese adults. previous studies are limited in terms of adjusting for variables such as sleep parameters and inflammation status. participants were asked to fill out a questionnaire on their lifestyle habits, health status, and clinical and laboratory assessments at the time of enrollment. anemia was assessed by measuring hb levels. next, insomnia was assessed using the chinese version of the athens insomnia scale (ais) with an eight-point questionnaire. the first five questions were related to the sleep procedure including sleep induction, night awakening, awakening early in the morning, total sleep duration, and sleep quality.
variables including age, physical activity, smoking and alcohol consumption, history of diabetes, blood pressure and cholesterol were adjusted in the analysis. the researchers also used chronic inflammation (high sensitivity c reactive protein ?1 mg/l) as a measure to distinguish iron-deficient and non-iron deficient cases of anemia. notably, the presence of prior anemia increased the risk of developing insomnia 6 years later by 32% compared to those without anemia. in addition, severe anemia significantly increased the odds of insomnia relative to mild and moderate anemia. next, in order to validate their findings, the researchers compared their observations with three other studies in a meta-analysis. their findings were indeed robust and suggest a strong correlation between anemia and insomnia. further, additional studies can help understand the molecular mechanisms and physiology behind this relationship along with the potential role of meis1” gao says.
in this large-scale community-based study of over 12,000 participants, we found that anemia was associated with a higher risk of having insomnia we’ve seen research showing iron-deficiency anemia is linked to lower sleep quality, and a small group of studies showing an association between results suggest that individuals with non-iron-deficient anemia are more likely to experience insomnia symptoms than those who are nonanemic., .
severe anemia was strongly linked to increased risk for insomnia while mild and moderate anemia was also associated with an elevated insomnia risk but to a lesser degree. men with anemia were found to be at greater risk for insomnia than women with anemia. a number of research studies indicate that the answer is yes, there is a strong correlation between iron deficiency and sleep problems. the results showed that ida affects sleep quality irrespective of psychological symptoms such as depression and anxiety. and also, it was shown that subjective left untreated, iron deficiency can lead to anemia and cause serious problems such as irregular heart beat and shortness of breath. although a lack of iron can notably, the presence of prior anemia increased the risk of developing insomnia 6 years later by 32% compared to those without anemia. in addition, severe, .
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