low iron and insomnia

recent studies have identified a gene that is associated with both insomnia and with iron-deficiency anemia, the most common form of anemia. iron-deficiency anemia can be caused by a lack of sufficient iron in diet, problems with iron absorption, blood loss, and in some cases, infection. in recent decades, rates of anemia in the us have grown substantially, nearly doubling between the years 2003-4 and 2011-12, according to research.




a handful of studies have demonstrated an association between iron-deficiency anemia and disrupted sleep, but we’re still in the early stages of understanding the impact that iron-deficiency has on adult sleep. most of the research on the relationship between iron-deficiency and sleep has focused on restless legs syndrome. michael breus, ph.d – the sleep doctor is a diplomate of the american board of sleep medicine and a fellow of the american academy of sleep medicine and one of only 168 psychologists to pass the sleep medical specialty board without going to medical school.

we thus examined whether adults with anemia had higher odds of having insomnia relative to those without anemia in a cross-sectional study and a meta-analysis. the presence of anemia was significantly associated with a higher likelihood of having insomnia in adults. further, the dose-dependent relationship between hemoglobin levels and insomnia was not explored. each question is scored on a scale of 0 to 3, with 0 being no problem of the corresponding sleep parameter and 3 being a serious problem (occurrence of greater than three times a week in the past month). logistic regression was used to calculate odds ratios (ors) and 95% confidence intervals (cis) for the association between anemia and insomnia. approximately 4.3% of the population was defined to have anemia based on hemoglobin levels and 15.2% of the population reported having insomnia [table 1].

this may lead to overestimating the association between anemia and insomnia [figure 3]. this finding is of clinical and public health importance due to the high prevalence of anemia and insomnia. [5,25] consistent with this notion, we found that the association between anemia and insomnia became stronger after we restricted our analysis to those participants without chronic inflammation. we observed a significant sex-difference in the anemia–insomnia relationship, and the association was more pronounced in men, relative to women. in this context, further prospective studies are warranted to elucidate the temporal relationship between anemia and insomnia. for example, the prevalence of anemia was lower, relative to the estimated 9.7% in a national survey. this research was supported by the start-up grant from the college of health and human development and the department of nutritional sciences, penn state university, and the institute for cyberscience seed grant program, penn state university.

we’ve seen research showing iron-deficiency anemia is linked to lower sleep quality, and a small group of studies showing an association between in this large-scale community-based study of over 12,000 participants, we found that anemia was associated with a higher risk of having insomnia insomnia, the inability to fall or stay asleep, is not a direct symptom of anemia, but sleep and alertness can be affected. symptoms of fatigue and chronic, .

results suggest that individuals with non-iron-deficient anemia are more likely to experience insomnia symptoms than those who are nonanemic. these results may have implications for insomnia treatment or the identification of underlying frailty in individuals with sleep problems. a number of research studies indicate that the answer is yes, there is a strong correlation between iron deficiency and sleep problems. iron plays a key role in the metabolism of monoamines in the brain thus iron deficiency leads to symptoms such as apathy, drowsiness, irritability and lack of severe anemia was strongly linked to increased risk for insomnia while mild and moderate anemia was also associated with an elevated insomnia a recent genome-wide analysis has revealed that the gene meis1 is linked with insomnia, which has also been implicated in restless leg syndrome and, .

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