lupus and gynecological problems

the .gov means it’s official. the site is secure. the https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. by acting via its cognate receptors erα and erβ expressed on immune cells, estrogen can modulate immune function in both the innate and adaptive immune responses.

unfortunately, reproductive function of young female patients with this disease is commonly compromised by different pathophysiologic processes. first, ovarian reserve is diminished even in the presence of mild disease suggesting a direct impact of the disease itself on ovarian function possibly due to ovarian involvement in the form of autoimmune oophoritis. therefore, sle patients exposed to cyclophosphamide have a much higher risk of developing infertility and premature ovarian failure than do the counterparts who are treated with other less toxic treatments. third, the functions of the hypothalamic pituitary ovarian axis are perturbed by chronic inflammatory state. we also discuss ovarian function and other reproductive outcomes in sle patients and the current strategies to preserve their fertility in the light of the most recent evidence-based findings of the clinical trials and molecular studies.

abstract: systemic lupus erythematosus (sle) is a systemic autoimmune disease most commonly involving skin, joints, and kidneys. an ob-gyn is uniquely placed in the health care continuum throughout the life cycle of a woman. notably, an ob-gyn often is the first physician to notice sle-related rash, swollen joints, cytopenias, or proteinuria in a patient and is the first to provide initial management.

human papillomavirus and associated cancer also are of concern in patients with sle. acog clinical is designed for easy and convenient access to the latest clinical guidance for patient care. note for life fellows: annual membership dues are waived but there is a discounted annual subscription fee of $95 for access to publications such as the green journal, practice bulletins, and committee opinions. for additional quantities, please contact [email protected] or call toll-free from u.s.: (800) 762-2264 or (240) 547-2156 (monday through friday, 8:30 a.m. to 5 p.m. et)

lupus is a chronic, autoimmune disease that can damage any part of the body, including the skin, joints, and organs inside the body. rashes, patchy hair loss and premature joint and heart disease can all occur with lupus. this article is based on reporting that features systemic lupus erythematosus (sle) is a chronic autoimmune systemic disease that mainly affects women of reproductive age. emerging data from recent, .

women with lupus have a higher rate of abnormal pap smears (a test that looks for precancers and cancer cells in the cervix) than women without lupus. make sure to get a pap smear every year. pap smears can help find cervical cancer early when it’s easier to treat. abstract: systemic lupus erythematosus (sle) is a systemic autoimmune disease most commonly involving skin, joints, and kidneys. women with lupus may be less active because of fatigue, joint problems, and muscle pain, and this also puts them at risk for heart disease. in impairment of the reproductive system of women with sle may result due to disease activity, autoantibodies, and through iatrogenic cytotoxic, .

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