mrna vaccine and fertility concerns

the .gov means it’s official. the site is secure. the https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. because of its severe impact, multiple covid-19 vaccines are being rapidly developed, approved and manufactured.

although several fertility societies have announced that covid-19 mrna vaccines are unlikely to affect fertility, there is no denying that the current evidence is very limited, which is one of the reasons for vaccine hesitancy in the population, especially in pregnant women. herein, we provide an in-depth discussion on the involvement of the male and female reproductive systems during sars-cov-2 infection or after vaccination. on the other hand, our review indicates that both men and women, especially pregnant women, have no fertility problems or increased adverse pregnancy outcomes after vaccination, and, in particular, the benefits of maternal antibodies transferred through the placenta outweigh any known or potential risks. © the author(s) 2021. published by oxford university press on behalf of european society of human reproduction and embryology. for permissions, please email:

on one hand, despite the low risk of infection in the male reproductive system or fetus, covid-19 could pose an enormous threat to human reproductive health. in the meantime, other individuals argued that the high co-expression of ace2 and ctsl in testis might increase testicular susceptibility to infection (kerslake et al., 2020). in addition to testis, the lung, kidney and spleen of this patient were also positive. (2020) found that the expression levels of proteases, such as tmprss2, tmprss4, ctsb and ctsl, significantly increased from the early secretory to mid-secretory (henarejos-castillo et al., 2020).

similarly, in studies of 400 000 women in the usa between 15 and 44 years of age with symptomatic covid-19, pregnant individuals were more likely to experience icu admission, intubation and death (zambrano et al., 2020). despite the serious threat of covid-19 to pregnant women, concerns about the safety and efficacy of mrna vaccines have still delayed most vaccinations in this group. the effects and benefits of mrna vaccines on pregnant women are undisputed. covid-19 poses a threat to the reproductive systems of both males and females. and all authors commented on previous versions of the manuscript.

the coronavirus disease 2019 (covid-19), which is caused by severe acute respiratory syndrome coronavirus 2 (sars-cov-2), has precipitated a meanwhile, given the potential damage of severe acute respiratory syndrome coronavirus 2 (sars-cov-2) to the reproductive system, some pregnancy after vaccination. many people have become pregnant after receiving a covid-19 vaccine, including some who got vaccinated during covid-19 vaccine, .

one concern emerged when a false report surfaced on social media claiming that getting vaccinated against covid-19 can cause infertility in two of our experts review some common myths circulating about the vaccine and clear up confusion with reliable facts. to address vaccine hesitancy based on concerns about fertility, this study assesses sperm parameters before and after mrna vaccine, .

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