this presentation highlights the need to consider mg in the differential diagnosis of unexplained dyspnea on exertion/rest. he became more dyspneic on immersing/standing in a swimming pool with water at the level of chest. the patient was discharged, but re-admitted in two weeks with recurrence of his symptoms. the patient was started on a high dose pyridostigmine (60 mg five times per day), with improvement in his dyspnea and exhaustion.
the patient was in remission on chronic maintenance prednisone of 40 mg per day and pyridostigmine 60 mg five times a day thereafter for two months. [table/fig-4] shows the characteristics of the patients reported in the literature and the present patient with isolated respiratory muscle weakness as the initial presentation of mg [2-5]. the diagnosis of mg can be challenging in certain group of patients. the two electrophysiologic tests used for the diagnosis of mg are repetitive nerve stimulation test and single fiber electromyography. ct scan of the chest in coronal and transverse views respectively shows bilateral interstitial reticulonodular opacities at lung bases slow repetitive stimulation (at a rate of 3 hz) of the right facial nerve after exercise, reveals greater than 10% decrement of the compound action muscle potential in almost all stimulus comparison of patients reported in the literature with isolated respiratory muscle weakness as the initial presentation of myasthenia gravis
it is important to identify the predictors of progression to mc and prognosis in the patients with mg with acute exacerbations. this study aimed to explore the predictors of progression to mc in the patients with mg with acute onset of dyspnea and their short-term and long-term prognosis. to find independent risk factors for progression to mc in the patients with acute onset of dyspnea, first dyspnea episodes of each patient were divided into two groups according to whether mc occurred, and the distribution of each predictor variable was compared between the two groups using a univariate analysis. we collected the clinical data from 86 patients with mg who had 111 visits to the emergency department for acute onset of dyspnea (table 1). of the 20 patients with multiple dyspnea episodes, seven patients did not experience mc in their first episodes but had mc in subsequent episodes.
we found that early-onset mg was an independent risk factor for progression to mc in the patients with mg with acute onset of dyspnea (table 2). further, our study also found that among the patients with mg with acute onset of dyspnea, respiratory infection was an independent risk factor for progression to mc. likewise, our study found that ivig was a protective factor for progression to mc in the patients with acute onset of dyspnea. the lower incidence of comorbidities and the higher incidence of thymoma in our patients compared with other studies may limit the generalization of the findings to all the patients. in conclusion, we demonstrated that early-onset mg and respiratory infection as a trigger were the independent risk factors for progression to mc in the patients with mg with acute onset of dyspnea, while the use of ivig prior to mechanical ventilation was a protective factor. the baseline characteristics of first acute dyspnea episodes of the patients with myasthenia gravis (mg) and comparison between myasthenic crisis (mc) and non-mc episodes.
isolated respiratory muscles weakness is an unusual presentation of myasthenia gravis (mg). we present a case of 49-year-old male with undiagnosed mg who objective: this study aimed to explore the predictors of progression to mc in the patients with mg with acute onset of dyspnea and their short- background: life-threatening myasthenic crisis (mc) occurs in 10–20% of the patients with myasthenia gravis (mg). it is important to identify, myasthenia gravis breathing test, myasthenia gravis breathing test, myasthenia gravis symptoms, myasthenia gravis shortness of breath treatment, myasthenia gravis mucus in throat.
the disorder is characterized by weakness and rapid fatigability of volun- tary muscles. patients with myasthenia gravis often complain of dyspnea, may be prone to respiratory tract infections, and not infrequently require prolonged periods of assisted ventilation. introduction. myasthenia gravis (mg), an autoimmune disorder affecting the neuromuscular junction, frequently provokes dyspnea as a result of respiratory muscle weakness. myasthenia gravis commonly presents as generalized muscle weakness. it is rare for the disease to selectively affect the respiratory muscles. weakness of the intercostal muscles and the diaphragm may result in carbon dioxide retention as a result of hypoventilation. respiratory failure usually occurs the most serious complications of myasthenia gravis is a myasthenia crisis. this is a condition of extreme muscle weakness, particularly of the diaphragm and, myasthenia gravis treatment, myasthenic crisis.
When you try to get related information on myasthenia gravis dyspnea, you may look for related areas. myasthenia gravis breathing test, myasthenia gravis symptoms, myasthenia gravis shortness of breath treatment, myasthenia gravis mucus in throat, myasthenia gravis treatment, myasthenic crisis.