the levels of hemoglobin and hematocrit increased with the severity of osa; only men with severe osa had significantly higher hemoglobin, hematocrit, and polycythemia compared with those in the control group (p < 0.01). the study was conducted in accordance with the declaration of helsinki and approved by the local ethics committee of ruijin hospital ( no.107). the percentage of sleep duration with spo2 < 90% (ts90) was also included.31 fasting blood samples were taken in the morning after psg monitoring. table 2 provides a summary of demographic and clinical characteristics in male and female participants according to the osa severity status.31 patients with osa were generally older and weighted, and more likely suffered from hypertension.
the roc curve analysis was performed for the cutoff values of hbg and hct to predict nocturnal hypoxemia defined with mean spo2 < 90% in osa patients. the data of this study showed that the mean spo2 decreased with the severity of osa, and mean spo2 in the severe osa group was the lowest among the three groups. as expected, according to the roc analysis in this study, the auc of hbg and hct in detecting mean spo2 < 90% was more than that in detecting the ahi. roc curves for hbg and hct to predict nocturnal hypoxemia defined with as mean spo2 < 90% in patients with obstructive sleep apnea.
the .gov means it’s official. the site is secure. the https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. however, the degree that osa contributes to clinically significant erythrocytosis is uncertain.
methods: we evaluated consecutive subjects with suspected untreated osa using multivariate analysis to test the associations between apnea-hypopnea index (ahi) and hematocrit. results: 1604 consecutive veterans (age 57.6 ± 13.4 years, 92% male) were included in the analysis with 77.4% diagnosed with osa. osa severity defined by ahi was not associated with hematocrit or clinically significant erythrocytosis. other factors including active tobacco, increased alcohol ingestion and exogenous testosterone therapy were associated with higher hematocrit. nocturnal oximetry may provide diagnostic utility in the evaluation of unexplained secondary polycythemia and polysomongraphy may be warranted in those with unexplained nocturnal hypoxemia and erythrocytosis.
patients with osa with polycythemia were found to have higher ahi, odi, and ts90, as well as lower mean spo2. in the subgroup analysis with conclusions: hematocrit levels and presence of erythrocytosis appear not associated with osa severity, but rather with hypoxemia as measured by awake and to a our results show that polycythemia is rarely seen in osa patients, and other potential causes of polycythemia should be evaluated before, .
secondary polycythemia is characterized by increased erythropoiesis stimulating factor (epo), being normal erythrocyte precursors in the bone marrow. the obstructive sleep apnea syndrome (osas) is characterized by intermittent hypoxia occur during sleep and can cause secondary polycythemia. there is a high prevalence of obstructive sleep apnea (osa) in the united states, with one-quarter of adults aged 30 to 70 years having osa. most clinicians consider osa as one of the causes of elevated hemoglobin (hb) – polycythemia, but this is based on anecdotal evidence and further work up is often not pursued. osa severity defined by ahi was not associated with hematocrit or clinically significant erythrocytosis. rather, awake oxygen saturation (-0.17 our patient had been diagnosed with obstructive sleep apnea several years why are “too many red blood cells”—a condition called erythrocytosis—a bad usually, polycythemia is found during routine blood tests and the physical symptoms are minimal, but those who have been diagnosed with it may, .
When you try to get related information on polycythemia and sleep apnea, you may look for related areas. .