lyme disease is caused by infection with the bacterium borrelia burgdorferi. this condition is called post-treatment lyme disease syndrome (ptlds). some experts believe that borrelia burgdorferi can trigger an “auto-immune” response causing symptoms that last well after the infection itself is gone.
finally, some believe that the symptoms of ptlds are due to other causes unrelated to the patient’s borrelia burgdorferi infection. although short-term antibiotic treatment is a proven treatment for early lyme disease, studiesexternal icon funded by the national institutes of health (nih) have found that long-term outcomes are no better for patients who received additional prolonged antibiotic treatment than for patients who received placebo. long-term antibiotic treatment for lyme disease has been associated with serious, sometimes deadly complications, as described in the links below. if you are considering long-term antibiotic treatment for ongoing symptoms associated with a lyme disease infection, please talk to your healthcare provider about the possible risks of such treatment.
in a study of 61 people treated for the bacteria that causes lyme disease, johns hopkins researchers conclude that fatigue… researchers report that a tick-borne illness known as post treatment lyme disease syndrome (ptlds) is a real disorder with real symptoms. roughly half were women and half were men, ranging in age between 18 and 82. also recruited were 26 healthy controls, also split nearly evenly between the sexes and about the same ages as the other group, with no clinical history of lyme disease symptoms and no antibodies to borrelia burgdorferi that would indicate past or current infection.
aucott says that between the two groups, few clinically significant differences existed in results of the physical exams and clinical laboratory tests, except for an abnormal inability to sense vibrations in some ptlds patients. these symptoms, aucott says, appear to reflect the significantly higher scores in a measure of depression and significantly lower scores on the sf-36, a widely used 36-item questionnaire that measures health-related quality of life. an estimated 300,000 people in the u.s. are diagnosed each year with lyme disease according to the centers for disease control and prevention.
although most cases of lyme disease can be cured with a 2- to 4-week course of oral antibiotics, patients can sometimes have symptoms of pain, fatigue, or researchers say that post-treatment #lymedisease syndrome is a real disorder with real symptoms. fatigue, pain, insomnia and depression seem most patients with lyme disease are cured by a 3–4 weeks’ course of antibiotics. however, a, .
along with these objective signs, persistent and recurrent symptoms such as fatigue, sleep disruption, arthralgia, myalgia, and headache are appropriate antibiotic therapy generally leads to a favorable outcome. still, unspecific persisting symptoms such as fatigue, myalgia, arthralgia or cognitive depending on the disease manifestation, the infection can usually be treated successfully with 2–4 weeks of oral antibiotic therapy. however,, .
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