rem related obstructive sleep apnea

objectives: the present study examined the association between osa during rem sleep and a composite cardiovascular endpoint in a community sample with and without prevalent cardiovascular disease. thus, the primary objective of the current investigation was to characterize the association between rem sleep–related osa and a composite cardiovascular endpoint in a community-based cohort of middle-aged and older persons with and without cardiovascular disease. of the 5,681 participants who completed the baseline examination and had data on cardiovascular events, 3,265 participants without osa during nrem sleep constituted the analysis sample for the current study. only those participants with at least 30 minutes of rem sleep were included in the analysis to allow for a representative estimate of the rem ahi. kaplan-meier survival curves as a function of rem ahi for the sample stratified are shown in figure 2. moderate and severe osa during rem sleep (rem ahi ≥15 events/h) were associated with a higher crude event rate for the composite cardiovascular endpoint.




stratified analyses showed a lack of an association between rem ahi and the composite cardiovascular endpoint in participants without prevalent cardiovascular disease. finally, no associations were identified between the frequency of arousals during rem sleep and cardiovascular disease. given the preponderance of evidence demonstrating an association between osa and cardiovascular outcomes in those with prevalent cardiovascular disease, it is surprising that the literature on the effects of continuous positive airway pressure (cpap) has not shown a consistent beneficial effect. limitations include the potential of residual confounding by very mild osa during nrem sleep and the small sample size in those with both prevalent cardiovascular disease and severe rem sleep–specific osa. ; analysis of data—r.n.a., c.c., j.s.k., and n.m.p.

methods: this was a prospective observational study of subjects with the following criteria: rem ahi≥15 events/hour; nrem ahi<5 events/hour; and ≥30 minutes rem sleep. outcome variables assessed at baseline and 1 year included: epworth sleepiness scale (ess); functional outcomes of sleep questionnaire (fosq); depression anxiety stress score (dass); psychomotor vigilance test (pvt) and cpap compliance. statistical analysis included paired t-tests and pearson correlation coefficient. outcome measures at baseline vs 1 year: ess 13.3±5.2 vs 8.1±4.8 au (p=0.01); fosq 13.0±3.6 vs 14.6±3.7 au (p=0.005); dass 19.4±10.0 vs 15.0±10.3 au (p=0.22); and pvt lapses 16.3±20.1 vs 13.1±21.5 (p=0.45).

change in ess moderately correlated with hours of cpap usage (r=0.59, p=0.03). following cpap treatment, they had improvements in sleepiness and quality of life. this is an ers international congress abstract. note: we only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. we do not capture any email address.

the term rem-related obstructive sleep apnea (osa) is used loosely by sleep clinicians when the polysomnogram (psg) reveals obstructive although sleep apnea is often more pronounced during rapid eye movement (rem) sleep, the term “rem-related” sleep apnea has been used to label sleep-disordered among those phenotypes, rem-related osa has been reported to account for 10–36% of patients with osa in sleep clinic cohorts (5), especially in patients, rem sleep apnea complications, rem sleep apnea complications, rem-related sleep apnea treatment, mild sleep apnea but severe in rem, treatment for rem apnea.

the term u201crem-relatedu201d osa has been coined to denote the occurrence of disordered breathing events that predominantly or exclusively manifest during rem sleepu2014an observation that is common in clinical practice and well recognized by healthcare professionals in sleep medicine. severe obstructive sleep apnea (osa) that occurs exclusively during rem sleep is associated with recurrent cardiovascular events in those with daily sleepiness may be stronger associated with apneas/hypopneas occurring in rem than nrem sleep. introduction. obstructive sleep apnea first, it is well established that respiratory events occurring during rem sleep have a longer duration and generate greater oxygen desaturations compared to, rem related sleep disorder, non rem sleep apnea.

When you try to get related information on rem related obstructive sleep apnea, you may look for related areas. rem sleep apnea complications, rem-related sleep apnea treatment, mild sleep apnea but severe in rem, treatment for rem apnea, rem related sleep disorder, non rem sleep apnea.