in 24-hour recordings, bp frequently features a “nondipping” profile, ie, <10% fall from day to night, which may increase cardiovascular risk and occurrence of major cardiovascular events in the nocturnal hours. today, it is commonly agreed that mean bp levels have a higher influence on cardiovascular risk than the 24-hour bp profile.2,16,17 in particular, nocturnal bp levels are the most useful predictors of cardiovascular disease.16,18–20 thresholds for normal bp values, assessed by abpm, have changed over time. along the same lines, a high mbps may be the effect of extreme dipping, such that it could be associated with increased cardiovascular risk due to very low nocturnal bp and not to high morning bp. due to the numerous, large, and rapid changes in bp during the night, information on bp in osa is heavily affected by the method used for its assessment.
however, it represents a clear advancement in the assessment of nocturnal bp in osa with respect to abpm. instead, elimination of respiratory disorders during sleep may be expected to prevent bp peaks and to reduce variability in bp during the night. current knowledge suggests that bp behavior in osa plays a role in the increased cardiovascular risk that is typical of this disorder, not only through its high diurnal and even more its nocturnal bp values but also through the characteristics of its variability. knowledge on pharmacological treatment of hypertension to be preferentially used in osa is still limited,127,128 and the few available data on chronotherapy for hypertension in osa are inconsistent. abpm measurement required a time exceeding the duration of an apnea cycle, ie, of an apnea and following ventilation.
although osa has been associated with a range of cardiovascular diseases, it has been etiologically linked most convincingly to hypertension. there is also there’s a wealth of research suggesting that sleep apnea and high blood pressure are a dangerous pair. obstructive sleep apnea, which occurs the apneic episodes in osa lead to an increase in bp, which further exposes the patient to cardiovascular and cerebrovascular risks. thus, identification of the, .
sudden drops in blood oxygen levels that occur during sleep apnea increase blood pressure and strain the cardiovascular system. having obstructive sleep apnea increases your risk of high blood pressure (hypertension). when you periodically stop breathing in your sleep, your body releases stress hormones. the american heart association explains that, with obstructive sleep apnea, these hormones can lead to high blood pressure, stroke, and heart disease. bp variability in osa patients with osa are characterized by a high prevalence of arterial hypertension, which may exceed 50%,36 and by high the airway blockages created by obstructive sleep apnea cause your blood pressure to increase, because your heart is working harder to get, .
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