these nocturnal events have the potential to increase pulmonary arterial pressure (pap) during sleep but also in the waking state. by contrast, in obesity hypoventilation syndrome (ohs) or overlap syndrome (the association of chronic obstructive pulmonary disease (copd) with obstructive sleep apnoea (osa)), nocturnal respiratory events contribute to the development of pulmonary hypertension (ph), which is often severe. in the latter circumstances, treatment of sbds is essential in order to improve pulmonary haemodynamics. there should be a strong suspicion of sbds in such a patient population; however, the precise indications for sleep studies and the type of recording remain to be specified. the diagnosis of osas in patients with pah or cteph should encourage treatment with continuous positive airway pressure (cpap).
in this review we will consider the current knowledge of the consequences of sbds on pulmonary haemodynamics in patients with and without chronic respiratory disease (group 3 of the clinical classification of ph) and the effect of treatments of respiratory events during sleep on ph. the prevalence and consequences of sbds in pah and cteph (groups 1 and 4 of the clinical classification of ph, respectively), as well as therapeutic options, will also be discussed. in these situations, it is important to treat apnoeas, hypopnoeas and nocturnal oxygen desaturations. conflict of interest: m. humbert has relationships with drug companies including actelion, bayer, gsk, merck and united therapeutics; in addition to being investigator in trials involving these companies, relationships include consultancy services and membership of scientific advisory boards. note: we only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail.
sleep-related breathing disorders are conditions of abnormal and difficult respiration during sleep, including chronic snoring and sleep obstructive sleep apnea (osa) is the most common category of sleep disordered breathing. the obstructive sleep apnea syndromes include those in which there is sleep-related breathing disorders or sleep-disordered breathing are characterized by abnormal respiration during sleep. they are grouped into obstructive, .
obstructive sleep apnea is the most common sleep-related breathing disorder. it causes you to repeatedly stop and start breathing while you the term breathing-related sleep disorder refers to a spectrum of breathing anomalies ranging from chronic or habitual snoring to upper the term ‘obstructive sleep apnoea’ (osa) refers to intermittent obstruction of the airway, irrespective of the presence of daytime symptoms. if symptoms result, .
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